Florence Nightingale Journal of Nursing
Research Article

Determination of the Influence of Peripheral Neuropathy Symptoms on Quality of Life in Breast Cancer Patients: A Cross-Sectional Study with Four Follow-Ups


Department of Internal Medicine Nursing, Hacettepe University, Faculty of Nursing, Ankara, Turkey


Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey


Department of Biostatistics, Hacettepe University, Ankara, Turkey

Florence Nightingale J Nurs 2023; 31: 75-81
DOI: 10.5152/FNJN.2023.22156
Read: 1089 Downloads: 550 Published: 01 June 2023

AIM: This study aims to evaluate the impact of peripheral neuropathy symptoms throughout with monthly follow-ups during 4 months of paclitaxel treatment.

METHODS: This prospective cross-sectional study was conducted with 79 patients. The study population consisted of female patients with breast cancer between August 2018 and January 2019. ‘’Chemotherapy-Induced Peripheral Neuropathy Assessment Tool’’ and ‘’EORTC C30 Cancer Quality of Life Questionnaire’’ were applied with four follow-ups. The study was undertaken in accordance with the STROBE checklist for cross- sectional studies.

RESULTS: The Chemotherapy-Induced Peripheral Neuropathy Assessment Tool except for the general activity subdimension were statistically significant in the ratings of second, compared to first; third compared to first and second; fourth compared to first, second, and third follow-up periods. The overall mean of the EORTC C30 Cancer Quality of Life Questionnaire, functioning, symptom, and global health status were statistically significant in the evaluations of second, compared with first; third compared with first and second; fourth compared with first, second, and third follow-up periods.

CONCLUSION: Findings from this study suggest that the increase in neuropathy symptoms during cures negatively affects the quality of life.

Cite this article as: Kurt, B., Sipahi Karslı, Z., Çakmak Öksüzoğlu, B. Ö., Öztürk, E., Demirörs, N., & Dağ, O. (2023). Determination of the influence of peripheral neuropathy symptoms on quality of life in breast cancer patients: A cross-sectional study with four follow-ups. Florence Nightingale Journal of Nursing, 31(2), 75-81.

EISSN 2687-6442