Florence Nightingale Journal of Nursing
Research Articles

Evaluation of the Incidence and Stage of Oral Mucositis in Patients Undergoing Hematopoietic Stem Cell Transplantation: A Retrospective Study

1.

Nurse Education Department, Akdeniz University Hospital, Antalya, Türkiye

2.

Internal Medicine Nursing Department, Akdeniz University, Faculty of Nursing, Antalya, Türkiye

3.

Bone Marrow Transplantation Unit, Akdeniz University Hospital, Antalya, Türkiye

Florence Nightingale J Nurs 2024; 32: 261-268
DOI: 10.5152/FNJN.2024.23049
Read: 147 Downloads: 74 Published: 31 October 2024

Aim: This study aims to retrospectively evaluate the incidence and stage of oral mucositis in patients undergoing hematopoietic stem cell transplantation.

Methods: A total of 102 patient records of patients hospitalized between 2014 and 2019 in the adult hematopoietic stem cell transplantation clinic of a tertiary university hospital in Turkey were evaluated. Data were collected through a retrospective evaluation of patient records. Records made according to the WHO Oral Toxicity Scale included in the patient records during hospitalization in the adult hematopoietic stem cell transplantation clinic were evaluated. Oral mucositis data from recordings were analyzed at baseline, and on days 5, 10, 15, and 30).

Results: 96.1% (n=98) of 102 patients developed oral mucositis; only 10.7% had Grade 3, and 2.7% had Grade 4. Oral mucositis development time was 8.28 ± 0.32 days, and recovery time was 14.25 ± 0.78 days. It was determined that smoking, diagnosis, transplantation type, and preparatory regimen affected the oral mucositis healing process.

Conclusion: While the incidence of oral mucositis in patients undergoing hematopoietic stem cell transplantation in our study was similar to be similar with the reported findings in the literature, the proportions of Grade 3 and 4 oral mucositis were lower in our study.

Cite this article as: Kara, H., Arıkan, F., Çil Kazan, S., Atay Turan, S., & Ören, R. (2024). Evaluation of the incidence and stage of oral mucositis in patients undergoing hematopoietic stem cell transplantation: A retrospective study. Florence Nightingale Journal of Nursing, 32(3), 261-268.

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