Today, we encounter entrepreneurship as an important dynamic element in all fields concerning improving human life quality and in accordance with this, the concepts of innovation and creativity arise. The importance of enterpreneurship lies in the fact that the entrepreneurs identify the needs of the society and transform this into investment and as a result, they transform this into societal wealth. The comprehensive scope of medicine sector ensures opportunity for the nurses to perform professional service and conduct various activities. In fact, entrepreneurship in nursing includes the acceptance and introduction of nurses. Today, nurse entrepreneurs are both owners and administrators of consulting services, education offices, home-health business agents, help-bound life and adult daily care associations, child care centers, public clinics, durable medical equipment companies, publishing companies and health care products companies.