Is There an Effect of Dietary Fructose on Development and Prognosis of Chronic Diseases?

Dietary sources of fructose are not onlyhoney, fruit, sucrose, but also high fructose corn syrup in various foods andbeverages. Total amount of daily fructose intake is rising by especiallyincreasing use of high fructose corn syrup in the food industry. Fructose canlead to obesity by contributing to high-energy intake and lipogenesis in thebody. Depending on the source of fructose, dose and duration, it was involvedin de-novo lipid synthesis. Fructose may increase the risk of insulinresistance, non-alcoholic fatty liver and kidney diseases by affecting bloodglucose and insulin levels. On the other hand, fructose may initiateinflammatory processes in the organism. In addition to these, fat or saltconsisting typical western type diet with high fructose consumption, canincrease the potential effect of fructose on chronic diseases. As a result,although it is not fully supported by clinical studies, it is thought that highamounts of fructose intake may increase the risk of chronic disease shown byexperimental studies. Also it should be noted that beside high fructose,typical western-style high-fat and high-salt diet may increase the risk ofchronic diseases such as obesity, cardiovascular diseases and worsen metabolicsyndrome parameters. Furthermore, synthetic fructose, is able to cause someadverse metabolic effects when taken in large amounts; consumption of highamounts of fructose by fruit or honey these negative effects can be either notseen or less observed based on the amount.

Cite this article as: Yürük, A. A. ve Nergiz-Ünal, R. (2019). Is there an effect of dietary fructose on development and prognosis of chronic diseases? FNJN Florence Nightingale Journal of Nursing, 27(1), 63-78.